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ESTRADIOL (ess-tra-DYE-ole)

Availability: In stock

Quantity Strength Unit Price Price Cart
28 Tablets Estrace 1mg $1.07 $29.99
84 Tablets Estrace 1mg $1.01 $84.99
28 Tablets Estrace 2mg $1.14 $31.99
84 Tablets Estrace 2mg $1.14 $95.99


Generic Estradiol sold under the brand name of Estrace is a type of estrogen, a female sex hormone, which is produced by the ovaries. It is used for the treatment of various menopausal symptoms such as hot flashes, dryness in vaginal region, burning, and irritation.  It is also used for preventing osteoporosis in postmenopausal women and for replacement of estrogen in females suffering from ovarian failure or other problems caused due to the lack of natural estrogen.

How does Estrace Works?

Estradiol shows its therapeutic action by interacting with a target cell receptor (Erα or Erβ) which is present within the cytoplasm of the cell. Once estradiol is bound to its receptor ligand, the receptor enters the nucleus of the target cell and persue the development of messenger RNA. This mRNA interacts with ribosomes to liberate a specific protein that shows the effects of estradiol on the cell.

What are the circumstances in which Estrace should not be consumed?

  • Avoid intake of this medicine if you are undergoing through vaginal bleeding due to any unknown reason.
  • If you are suffering from renal or hepatic impairment, then you should not take this medicine.
  • Consumption of this medicine should be avoided in case of blood-clotting disorder.
  • A person with the history of heart attack or stroke should not take this medicine.
  • Intake of this medicine should be avoided, if you are sensitive towards generic Estradiol.


Which medicines should not be consumed with Estrace?

  • Barbiturates like Phenobarbital
  • Anti epileptic drugs such as Carbamazepine, Phenytoin
  • Anti-tuberculosis drugs like Ethambutol, Rifampin
  • Antifungal drugs such as Ketoconazole, Itraconazole
  • HIV protease inhibitor: Ritonavir, Saquinavir


How to store Estrace?

This medicine should be stored at a room temperature of 25-300C. This medicine should be kept in a cool, dry and hygienic place away from direct heat, sunlight and moisture.


What is the recommended dose of Estrace?

  • Adult Dose for Postmenopausal Symptoms: A dose of 0.45 mg to 2 mg should be consumed orally once in a day.
  • Adult Dose for Atrophic Urethritis: A dose of 1 to 2 mg should be consumed via mouth, one time in a day.
  • Adult Dose for Primary Ovarian Failure: A female should consume a recommended dose of 1 to 2mg, once in a day along with water.
  • Adult Dose for Osteoporosis: A prescribed dose of 0.5mg should be swallowed by a female via mouth along with a glass of water.


What are the side effects exhibited by Estrace?

Pain in the breast, headache, vaginal itching or discharge, changes in your menstrual periods, light vaginal bleeding or spotting, thinning scalp hair, nausea, vomiting, bloating and stomach cramps, loss of appetite, constipation, increased urination, muscle pain or weakness, joint pain, confusion, and feeling tired.


What are the safety tips that should be followed while consuming Estrace?

  • Breast feeding females should consume this medicine by consulting a doctor as it passes through the milk and decreases the quantity of breast milk.
  • You should use birth control methods to prevent pregnancy while consuming this medicine.
  • Consumption of grape fruit or grape juice should be avoided as it may lead to various unwanted side effects. 

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